In the ever-evolving landscape of growth equity and venture capital, 2025 has marked a decisive shift in investment strategies. At LeverVenture, we've observed a clear trend: cross-border investments are no longer just an option—they're becoming essential for funds seeking alpha in an increasingly globalized ecosystem.

The numbers tell a compelling story. Cross-border transactions increased by 43% in the first half of 2025 compared to the same period last year, with particularly strong flows between North America and Europe. But what's driving this surge, and why are these strategies outperforming domestic-only approaches?

The Macroeconomic Catalysts

Several macroeconomic factors have converged to create the perfect environment for cross-border strategies:

  1. Divergent monetary policies across major economies have created arbitrage opportunities for savvy investors
  2. Currency stabilization after years of volatility has reduced FX risk
  3. Regional growth differentials have opened windows for tactical capital deployment

"The traditional U.S.-centric investment approach is giving way to a more nuanced global strategy," notes Marcus Thompson, Managing Director at PitchBook. "Growth equity firms that recognized this shift early are now reaping substantial rewards."

This shift isn't merely theoretical. According to recent Preqin data, cross-border growth equity funds have delivered an average IRR of 24.2% over the past 18 months, outperforming U.S.-only funds by approximately 530 basis points.

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Europe's Renaissance: Beyond Valuation Arbitrage

For years, Europe was viewed primarily as a value play—the same business models as in the U.S., but at lower multiples. In 2025, that narrative has fundamentally changed.

Europe's appeal now stems from three distinct advantages:

1. Sectoral Excellence and Innovation Hubs

Europe has developed world-leading clusters in several high-growth sectors:

  • Healthcare and Life Sciences: The BioNTech effect has catalyzed biotech ecosystems across Germany, Switzerland, and the Nordics
  • Climate Tech: European companies lead in carbon capture, green hydrogen, and energy storage technologies
  • Enterprise Software: B2B SaaS companies in the Nordics, Benelux, and UK are scaling globally at accelerating rates

The European tech ecosystem has matured significantly. As we noted in our previous analysis of growth trends, European startups raised €73.7 billion in 2024, the highest annual figure on record despite global headwinds.

2. Regulatory Advantage and First-Mover Benefits

Europe's early adoption of comprehensive AI, data, and climate regulations has created unexpected opportunities. Companies that have mastered these regulatory frameworks now enjoy significant advantages when expanding globally.

The European AI Act, for instance, has established clear guidelines that have actually accelerated commercial adoption of AI technologies in regulated industries like finance, healthcare, and transportation. U.S. investors are increasingly seeking exposure to European companies that have already navigated these regulatory hurdles.

3. Talent Density at Competitive Costs

The talent advantage cannot be overstated. Major European tech hubs now boast engineering and technical talent pools comparable to Silicon Valley, but at 30-40% lower costs. This fundamental advantage drives stronger unit economics and extended runways.

According to Harvard Business Review, companies with significant European R&D operations demonstrate 22% higher capital efficiency than their pure U.S. counterparts.

Asia-Pacific: The Next Frontier

While Europe captures headlines, sophisticated investors are also increasing allocations to Asia-Pacific markets, where cross-border investments surged by an impressive 86% year-over-year in Q2 2025, reaching $6.7 billion.

Japan has emerged as a particularly attractive destination, with foreign investors targeting multifamily assets and office sectors. Meanwhile, South Korea's industrial and logistics investments have quadrupled in the first half of 2025 compared to the same period last year.

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At LeverVenture, we've been actively exploring these markets through our cross-border investment framework, which emphasizes:

  • Local partnership networks
  • Sector-specific expertise
  • Regulatory navigation capabilities
  • Cultural competence

Strategic Considerations for Successful Cross-Border Investing

Our experience has taught us that successful cross-border strategies require more than just capital allocation decisions. They demand a fundamentally different operational approach.

Building Multi-Regional Operational Expertise

At LeverVenture, we've built dedicated teams with specific regional expertise. This isn't just about having offices in different locations—it's about cultivating deep local knowledge, relationships, and cultural understanding.

"You can't parachute in with a Silicon Valley playbook and expect success," explains Sarah Chen, Partner at LeverVenture overseeing European investments. "Each ecosystem has its own rhythms, talent dynamics, and growth patterns."

Value Creation Across Borders

The most successful cross-border strategies aren't just about capital arbitrage—they create value by facilitating market entry, talent acquisition, and global scaling. Our portfolio companies benefit from:

  • Access to our global customer networks
  • Regulatory navigation expertise
  • Talent recruitment across geographies
  • Localization strategies for product and go-to-market

Navigating Cultural Differences

Cultural intelligence remains critical. We've developed a proprietary framework for assessing cultural fit and identifying potential friction points before they impact operations.

"Understanding cultural nuances in decision-making, communication styles, and risk tolerance can mean the difference between a successful cross-border partnership and a costly misalignment," notes our team's research on operational excellence.

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Sectoral Opportunities Driving Cross-Border Strategies

Different sectors present unique cross-border opportunities:

Sector Key Cross-Border Trend Notable Regions
Enterprise SaaS Product-led growth companies expanding from Europe to U.S. Nordics, UK, Germany
Climate Tech U.S. capital flowing to European innovation Nordics, DACH regions
Life Sciences Bi-directional flows leveraging regulatory pathways Boston-UK-Switzerland corridor
Fintech Regulatory arbitrage and specialized ecosystems UK, Singapore, Lithuania
Deep Tech Research collaboration and commercialization Israel, France, Canada

The LeverVenture Approach

At LeverVenture, we've structured our investment strategy to capitalize on these cross-border opportunities. Our approach includes:

  1. Dedicated cross-border investment teams with deep local expertise
  2. Global operating partners who understand scaling challenges across markets
  3. Regulatory navigation experts who can turn compliance into competitive advantage
  4. Cultural integration specialists who minimize friction in cross-border operations

This structured approach has delivered tangible results. Our cross-border portfolio companies have achieved 37% faster international expansion and 42% higher revenue growth compared to regional-only players.

Looking Forward: The Future of Cross-Border Strategies

As we move through 2025 and beyond, several trends will shape cross-border investment strategies:

  1. Regulatory convergence in key areas like AI, data protection, and climate will create more predictable expansion pathways
  2. Remote work normalization will accelerate talent distribution and create truly global companies from day one
  3. Specialized ecosystems will continue to develop around specific technologies and sectors
  4. Geopolitical considerations will increasingly influence investment flows and partnership strategies

The winners in this environment will be investors who combine global perspective with local execution capabilities—precisely the approach we've built at LeverVenture.

Conclusion: The Imperative for Cross-Border Strategies

For growth equity and venture investors, cross-border strategies have evolved from opportunistic plays to strategic imperatives. The data is clear: firms with sophisticated cross-border capabilities are consistently outperforming their domestic-only counterparts.

The key is moving beyond simplistic geographic diversification to building true cross-border expertise—understanding local ecosystems, creating value across borders, and helping portfolio companies navigate the complexities of global expansion.

As we noted in our previous analysis of market trends, the most successful investors in 2025 are those who can identify excellence wherever it exists, apply capital efficiently across borders, and create operational value through their global networks and expertise.

At LeverVenture, we remain committed to this approach—finding exceptional companies regardless of geography and helping them achieve their global potential.


This article is part of our ongoing series on growth equity and venture capital trends. For more insights, visit our Insights page or contact our team to discuss cross-border investment opportunities.

Categories: Growth Equity, Venture Capital, Finance